One of dermatology's most effective moisturizing ingredients. Urea is excellent for both hydration and treating rough, thickened skin, with its effects varying depending on concentration.
Clinical evidence
Not yet rated
Effectiveness (provisional)
5 out of 5
Typical concentration
2–10%: Hydration 10–20%: Softening rough skin 20–40%: Intensive keratolytic treatment (often for feet or calluses)
Suitable for
Most skin types.
How often
—
Primary benefits
Hydration
Softens rough skin
Strengthens barrier
Gentle exfoliation (higher concentrations)
What it does
Urea is naturally present in the skin as part of the Natural Moisturizing Factor (NMF). At lower concentrations it functions primarily as a humectant, while higher concentrations also help soften and exfoliate thickened skin.
Use with caution
No specific layering warnings recorded.
Pregnancy and breastfeeding
Not assessed. Speak to your healthcare provider.
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