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Professional beauty advice. Honest reviews. Smarter beauty choices.

Proteolytic Enzyme

Papain

One of the classic enzyme exfoliants that provides gentle resurfacing with minimal irritation.

Clinical evidence
Not yet rated
Effectiveness (provisional)
4 out of 5
Typical concentration
Usually proprietary.
Suitable for
Most skin types.
How often

Primary benefits

  • Gentle exfoliation
  • Improves skin smoothness
  • Brightens dull skin
  • Softens rough texture

What it does

Papain is an enzyme extracted from papaya (Carica papaya). It breaks down keratin proteins that bind dead skin cells together, allowing them to be removed more easily.

Use with caution

When combining with retinoids or exfoliating acids, monitor for irritation and avoid excessive exfoliation.

Pregnancy and breastfeeding

Generally considered safe for topical cosmetic use.

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